Has more prominent analgesic action than other NSAIDs which makes it more useful as an analgesic than as an anti-inflammatory or anti-pyretic. Action is mainly due to inhibition of prostaglandin synthesis. No action at the opioid receptors.

Short term management of acute pain, pain associated with surgical procedures.

Coagulation disorders & peptic ulcer.

Nausea, vomiting, epigastric distress, diarrhoea, headache, drowsiness, dizziness, skin rash & sweating.

Hepatic and renal dysfunction. Not to be used in children. In GI disease to be used with caution.

Anticoagulants : May prolong prothrombin time.

Beta-blockers :  Antihypertensive effect may be impaired.

Cyclosporine :  Nephrotoxicity of both agents may be increased.

Lithium :  Serum lithium levels may be increased resulting in toxicity.

Hydantoins :  Serum hydantoin levels increased resulting in increased efficacy and toxic effects.

Methotrexate :  Risk of methotrexate toxicity increased.

Aspirin :  Plasma concentration of ketorolac may be decreased and may increase the incidence of GI effect.

Adults : Initially 30-60mg by I.M., then 10-30mg every 4-6 hours. Maximum 150mg for 1st day and 120mg / day thereafter.

Children :  Not recommended. 

4-6 hours. 

30mg / ml,  1ml vial,  Injection
60mg / ml,  1ml vial,  Injection.

  
*  for the use of a registered Medical practitioner or a Hospital or a Laboratory only.

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