Ethionamide   -  Antituberculous  /  Antileprotic

  
Manufacturers of Ethionamide Tablets - Anti-Tuberculosis, antibiotic drug.

  

 Action :

Bacteriostatic against M.tuberculosis. Also active against atypical mycobacteria such as M.kansasii, and some strains of M.avium complex, and M.leprae.

  

 Indication :

Tuberculosis when other drugs are ineffective or contraindicated. In regimens of leprosy.

  

 Pharmaco-Kinetics :

After oral administration it is well absorbed from GI tract and widely distributed throughout body tissue and CSF. It crosses the placenta and is metabolised. Less than 1% of the drug is excreted in urine.

  

 Contraindication :

Hepatic impairment and hypersensitivity.

  

 Adverse-Effects :

Nausea, vomiting, anorexia, hepatotxicity, drowsiness, depression, peripheral neuritis, headache, skin rash, menorrhagia, acne, alopecia, hypertension, convulsion, diplopia.

  

 Special Precaution :

To assess liver function periodically.

  

 Interactions :

No known interactions.

  

 Dosage :

Adults

:

Resistant tuberculosis

:

0.5-1g daily after meals in 2-3 div. doses along with other antitubercular drugs. Max. 1g daily.

Multibacillary leprosy

:

5mg/kg as single daily oral dose.

Children

:

Resistant tuberculosis

:

15-20mg/kg daily div. 12 hrly. Max. 1g daily.

Multibacillary leprosy

:

Same as adult on weight basis.

    

 Onset of action :

30 - 60 mins. 

  

 Duration of action :

12-16 hours. 

  

 Strength & Packing :

250mg per tablet,  10 caps per box (strip packing) 

  
*  for the use of a registered Medical practitioner or a Hospital or a Laboratory only.

  

  

Export Product List


[Go Back to the Export product list]

   
  

   

  

   

Disclaimer : This guide is provided for information purposes only, and for use of a registered medical practitioner or a hospital or a laboratory only. The authors, webmaster, or respective references / links are no way responsible for the content of the information. Although a concerted effort has been made to ensure the validity of the information contained in this document, we give no assurance for the accuracy of the information in this documents.