Dopamine  HCl  -  Anti-Shock / Cardiovascular  drug

  
Manufacturers of Dopamine HCl Injection, an anti-shock - cardiovascular drug, used in treatment of chronic cardiac failure.

  

 Action :

Increases heart  rate and force of contraction. At low infusion rates vasodilatation occurs in the renal mesenteric, coronary and cerebral beds. At higher rates vasoconstriction in skeletal muscles and a rise in BP. Vasoconstriction also in renal and mesenteric areas.

  

 Indication :

Shock syndrome due to MI, trauma, septicaemia heart surgery, renal failure, chronic cardiac failure.

 

 Pharmaco-Kinetics :

It is given by I.V. infusion because it has a short plasma half life.

   

 Contraindication :

Atrial or ventricular tachyarrhythmias hyperthyroidism, phaeochromocytoma.

  

 Adverse-Effects :

Nausea, vomiting, atopic beats, anginal pain, tachycardia, palpition, widened QRS.

  

 Special Precaution :

Occlusive vascular disease, hypovolaemia.

  

 Interactions :

Guanethidine

:

Antihypertensive effect of guanethidine may be partially reversed.

Halogenated hydrocarbon anaesthetics

:

 May sensitize the myocardium to effects of catecholamines resulting in serious arrhythmias.

MAO/s

:

Increase the pressure response to dopamine by six-fold to twentyfold.

Furazolidone

:

Same effect as MAO/s as it also possesses MAO inhibitor activity.
Oxytocic drugs : May cause severe persistent hypertension.
Phenytoin : May lead to seizures, severe hypotension and bradycardia.

   

 Dosage :

Adults : 2mcg - 50mcg / kg  body-weight / min.  as  I.V. infusion. 

  

 Duration of action :

Half-life 2 mins. 

    

 Strength & Packing :

  

  
*  for the use of a registered Medical practitioner or a Hospital or a Laboratory only.

  

  

Export Product List


[Go Back to the Export product list]

   
  

   

  

  

Disclaimer : This guide is provided for information purposes only, and for use of a registered medical practitioner or a hospital or a laboratory only. The authors, webmaster, or respective references / links are no way responsible for the content of the information. Although a concerted effort has been made to ensure the validity of the information contained in this document, we give no assurance for the accuracy of the information in this documents.