Cycloserine  -  Anti T.B. Antibiotic

 

"Tuberculosis - A Global Emergency 
Use Cycloserine caps a second line tuberculosis antibiotic drug, for a new lease of life."

  
 Its low indigence of resistance is suitable for majority of patients and it remains active till completely excreted, thus provides sustained Anti-T.B. cover.

This product is manufactured under strict quality control and is available in small retailers pack of 12 caps per box, at very competitive prices. Should you have bulk requirements for this product then we could also provide you this product as per Tailor-made manufacturing (as per your standards, packing, and private labeling). 

We are also in a position to meet your requirement of product documents for tender or registration purposes and your requirements for bulk D-Cycloserine raw material in U.S.P. / B.P. standards.

  
Cycloserine Capsules - (D-cycloserine), Anti-tuberculosis antibiotic drug.

  

 Action :

A second line antituberculous drug effective against M.tuberculosis. It is a competitive antagonist of the racemase enzyme involved in bacterial cell wall synthesis. It is also active against other mycobacteria such as M.fortuitum, M.Kansasii and M.malmoense. 

  

 Indication :

For retreatment of multi drug resistant tuberculosis with other primary drugs. It may be used for treatment of Acute U.T.I. caused by susceptible microorganisms. 

  

 Pharmaco-Kinetics :

After oral administration it is rapidly absorbed and is distributed well in various body tissues including CSF. It is excreted largely unchanged by glomerular filtration. 

  

 Contraindication :

Hypersensitivity, epilepsy, psychosis, depression, renal failure. In alcoholics.

  

 Adverse-Effects :

Headache, skin rash, nervousness, dizziness, drowsiness, vertigo, confusion, seizures, tremors and psychotic states. 

  

 Special Precaution :

It may cause Vit. B12 or / and folic acid deficiency which may lead to megaloblastic anaemia. Patients who receive more than 500mg per day should be observed for CNS toxicity. In children safety and dosage has not been established. 

  

 Interactions :

Alcohol : Incompatible. Increases the possibility and risk of epileptic episodes.
Isoniazid : May result in increased cycloserine CNS side effects notably dizziness. 

  

 Dosage :

Adults : 500mg - 1g daily. 

  

 Onset of action :

30 - 60 mins. 

  

 Duration of action :

12-16 hours.  

  

 Strength & Packing :

250mg per capsule, 12 caps per box (strip packing) 

  
*  for the use of a registered Medical practitioner or a Hospital or a Laboratory only.

  

  

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Shree  Ganesh  Pharmaceuticals
Mumbai - India.
  
Web site :  http://www.sgpharma.com             E-mail  :  exports@sgpharma.com

  
Disclaimer : This guide is provided for information purposes only, and for use of a registered medical practitioner or a hospital or a laboratory only. The authors, webmaster, or respective references / links are no way responsible for the content of the information. Although a concerted effort has been made to ensure the validity of the information contained in this document, we give no assurance for the accuracy of the information in this documents.